The role of regulatory CD4+CD25+high T-lymphocytes and their functional activity in the development of type 1 diabetes mellitus

Type 1 diabetes mellitus (DM1) is associated with compromised (defective) immunologic tolerance to autoantigens and selective destruction of pancreatic B-cells by CD4+ (effector) and CD8 (cytotoxic) lymphocytes. The mechanisms of autotolerance involve CD4+CD25+high T-regulatory cells (Treg) whose su...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Tatiana Vasil'evna Nikonova, Pavel Vasil'evich Apanovich, Elena Vladimirovna Pekareva, Vera Anatol'evna Gorelysheva, Sergey Alexandrovich Prokof'ev, Alexander Vasil'evich Karpukhin, Ivan Ivanovich Dedov
Formato: article
Lenguaje:EN
RU
Publicado: Endocrinology Research Centre 2010
Materias:
Acceso en línea:https://doaj.org/article/d25393636268490b95fce9d3182b0abb
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!