Bile acids contribute to the development of non-alcoholic steatohepatitis in mice

Background & Aims: Through FXR and TGR5 signaling, bile acids (BAs) modulate lipid and glucose metabolism, inflammation and fibrosis. Hence, BAs returning to the liver after enteric secretion, modification and reabsorption may contribute to the pathogenesis of non-alcoholic steatohepatitis (...

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Autores principales: Justine Gillard, Laure-Alix Clerbaux, Maxime Nachit, Christine Sempoux, Bart Staels, Laure B. Bindels, Anne Tailleux, Isabelle A. Leclercq
Formato: article
Lenguaje:EN
Publicado: Elsevier 2022
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FXR
Acceso en línea:https://doaj.org/article/d288e103d667458db40d774aae2af880
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