Bile acids contribute to the development of non-alcoholic steatohepatitis in mice

Bile acids contribute to the development of non-alcoholic steatohepatitis in mice

Background & Aims: Through FXR and TGR5 signaling, bile acids (BAs) modulate lipid and glucose metabolism, inflammation and fibrosis. Hence, BAs returning to the liver after enteric secretion, modification and reabsorption may contribute to the pathogenesis of non-alcoholic steatohepatitis (...

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Bibliographic Details
Main Authors: Justine Gillard, Laure-Alix Clerbaux, Maxime Nachit, Christine Sempoux, Bart Staels, Laure B. Bindels, Anne Tailleux, Isabelle A. Leclercq
Format: article
Language:EN
Published: Elsevier 2022
Subjects:
NAFLD
NASH
TGR5
FXR
metabolic syndrome
Diseases of the digestive system. Gastroenterology
RC799-869
Online Access:https://doaj.org/article/d288e103d667458db40d774aae2af880
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https://doaj.org/article/d288e103d667458db40d774aae2af880

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