Class A scavenger receptor 1 (MSR1) restricts hepatitis C virus replication by mediating toll-like receptor 3 recognition of viral RNAs produced in neighboring cells.

Persistent infections with hepatitis C virus (HCV) may result in life-threatening liver disease, including cirrhosis and cancer, and impose an important burden on human health. Understanding how the virus is capable of achieving persistence in the majority of those infected is thus an important goal...

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Auteurs principaux: Hiromichi Dansako, Daisuke Yamane, Christoph Welsch, David R McGivern, Fengyu Hu, Nobuyuki Kato, Stanley M Lemon
Format: article
Langue:EN
Publié: Public Library of Science (PLoS) 2013
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Accès en ligne:https://doaj.org/article/d2ab2daf2ac74901aa2fab9aed3dd504
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