Parity associates with chromosomal damage in uterine leiomyomas

Parity associates with chromosomal damage in uterine leiomyomas

Many factors have been associated with chromosomal damage, including mechanical forces in a constrained cellular environment. Here the authors reveal an association between parity and chromosomal damage by analysing karyotypes of 1946 uterine leiomyomas.

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Autores principales: Heli Kuisma, Simona Bramante, Kristiina Rajamäki, Lauri J. Sipilä, Eevi Kaasinen, Jaana Kaukomaa, Kimmo Palin, Netta Mäkinen, Jari Sjöberg, Nanna Sarvilinna, Jussi Taipale, Liisa Kauppi, Manuela Tumiati, Antti Hassinen, Janne Pitkäniemi, Jyrki Jalkanen, Sanna Heikkinen, Annukka Pasanen, Oskari Heikinheimo, Ralf Bützow, Niko Välimäki, Lauri A. Aaltonen
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/d2e867958c8a4229a73872634dd5e339
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spelling oai:doaj.org-article:d2e867958c8a4229a73872634dd5e3392021-12-02T15:16:10ZParity associates with chromosomal damage in uterine leiomyomas10.1038/s41467-021-25806-x2041-1723https://doaj.org/article/d2e867958c8a4229a73872634dd5e3392021-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-25806-xhttps://doaj.org/toc/2041-1723Many factors have been associated with chromosomal damage, including mechanical forces in a constrained cellular environment. Here the authors reveal an association between parity and chromosomal damage by analysing karyotypes of 1946 uterine leiomyomas.Heli KuismaSimona BramanteKristiina RajamäkiLauri J. SipiläEevi KaasinenJaana KaukomaaKimmo PalinNetta MäkinenJari SjöbergNanna SarvilinnaJussi TaipaleLiisa KauppiManuela TumiatiAntti HassinenJanne PitkäniemiJyrki JalkanenSanna HeikkinenAnnukka PasanenOskari HeikinheimoRalf BützowNiko VälimäkiLauri A. AaltonenNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-10 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Heli Kuisma
Simona Bramante
Kristiina Rajamäki
Lauri J. Sipilä
Eevi Kaasinen
Jaana Kaukomaa
Kimmo Palin
Netta Mäkinen
Jari Sjöberg
Nanna Sarvilinna
Jussi Taipale
Liisa Kauppi
Manuela Tumiati
Antti Hassinen
Janne Pitkäniemi
Jyrki Jalkanen
Sanna Heikkinen
Annukka Pasanen
Oskari Heikinheimo
Ralf Bützow
Niko Välimäki
Lauri A. Aaltonen
Parity associates with chromosomal damage in uterine leiomyomas
description Many factors have been associated with chromosomal damage, including mechanical forces in a constrained cellular environment. Here the authors reveal an association between parity and chromosomal damage by analysing karyotypes of 1946 uterine leiomyomas.
format article
author Heli Kuisma
Simona Bramante
Kristiina Rajamäki
Lauri J. Sipilä
Eevi Kaasinen
Jaana Kaukomaa
Kimmo Palin
Netta Mäkinen
Jari Sjöberg
Nanna Sarvilinna
Jussi Taipale
Liisa Kauppi
Manuela Tumiati
Antti Hassinen
Janne Pitkäniemi
Jyrki Jalkanen
Sanna Heikkinen
Annukka Pasanen
Oskari Heikinheimo
Ralf Bützow
Niko Välimäki
Lauri A. Aaltonen
author_facet Heli Kuisma
Simona Bramante
Kristiina Rajamäki
Lauri J. Sipilä
Eevi Kaasinen
Jaana Kaukomaa
Kimmo Palin
Netta Mäkinen
Jari Sjöberg
Nanna Sarvilinna
Jussi Taipale
Liisa Kauppi
Manuela Tumiati
Antti Hassinen
Janne Pitkäniemi
Jyrki Jalkanen
Sanna Heikkinen
Annukka Pasanen
Oskari Heikinheimo
Ralf Bützow
Niko Välimäki
Lauri A. Aaltonen
author_sort Heli Kuisma
title Parity associates with chromosomal damage in uterine leiomyomas
title_short Parity associates with chromosomal damage in uterine leiomyomas
title_full Parity associates with chromosomal damage in uterine leiomyomas
title_fullStr Parity associates with chromosomal damage in uterine leiomyomas
title_full_unstemmed Parity associates with chromosomal damage in uterine leiomyomas
title_sort parity associates with chromosomal damage in uterine leiomyomas
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/d2e867958c8a4229a73872634dd5e339
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AT kristiinarajamaki parityassociateswithchromosomaldamageinuterineleiomyomas
AT laurijsipila parityassociateswithchromosomaldamageinuterineleiomyomas
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