Infection-Induced Intestinal Dysbiosis Is Mediated by Macrophage Activation and Nitrate Production

Infection-Induced Intestinal Dysbiosis Is Mediated by Macrophage Activation and Nitrate Production

ABSTRACT Oral infection of C57BL/6J mice with Toxoplasma gondii results in a marked bacterial dysbiosis and the development of severe pathology in the distal small intestine that is dependent on CD4+ T cells and interferon gamma (IFN-γ). This dysbiosis and bacterial translocation contribute to the d...

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Bibliographic Details
Main Authors: Shuai Wang, Ayah El-Fahmawi, David A. Christian, Qun Fang, Enrico Radaelli, Longfei Chen, Megan C. Sullivan, Ana M. Misic, Jodi A. Ellringer, Xing-Quan Zhu, Sebastian E. Winter, Christopher A. Hunter, Daniel P. Beiting
Format: article
Language:EN
Published: American Society for Microbiology 2019
Subjects:
gut microbiota
microbiome
Toxoplasma
dysbiosis
nitric oxide
Microbiology
QR1-502
Online Access:https://doaj.org/article/d2ef25ef76e04b01ad8ae75f8454e93f
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https://doaj.org/article/d2ef25ef76e04b01ad8ae75f8454e93f

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