Infection-Induced Intestinal Dysbiosis Is Mediated by Macrophage Activation and Nitrate Production
ABSTRACT Oral infection of C57BL/6J mice with Toxoplasma gondii results in a marked bacterial dysbiosis and the development of severe pathology in the distal small intestine that is dependent on CD4+ T cells and interferon gamma (IFN-γ). This dysbiosis and bacterial translocation contribute to the d...
Saved in:
Main Authors: | Shuai Wang, Ayah El-Fahmawi, David A. Christian, Qun Fang, Enrico Radaelli, Longfei Chen, Megan C. Sullivan, Ana M. Misic, Jodi A. Ellringer, Xing-Quan Zhu, Sebastian E. Winter, Christopher A. Hunter, Daniel P. Beiting |
---|---|
Format: | article |
Language: | EN |
Published: |
American Society for Microbiology
2019
|
Subjects: | |
Online Access: | https://doaj.org/article/d2ef25ef76e04b01ad8ae75f8454e93f |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Dysbiosis and Its Discontents
by: Katarzyna B. Hooks, et al.
Published: (2017) -
Dysbiosis in the Human Microbiome of Cholangiocarcinoma
by: Benchen Rao, et al.
Published: (2021) -
The Genotoxin Colibactin Shapes Gut Microbiota in Mice
by: Sophie Tronnet, et al.
Published: (2020) -
Gut Microbiota Dysbiosis Is Associated with Altered Bile Acid Metabolism in Infantile Cholestasis
by: Yizhong Wang, et al.
Published: (2019) -
Rectal Swabs from Critically Ill Patients Provide Discordant Representations of the Gut Microbiome Compared to Stool Samples
by: Katherine Fair, et al.
Published: (2019)