Systems analysis of MVA-C induced immune response reveals its significance as a vaccine candidate against HIV/AIDS of clade C.

Systems analysis of MVA-C induced immune response reveals its significance as a vaccine candidate against HIV/AIDS of clade C.

Based on the partial efficacy of the HIV/AIDS Thai trial (RV144) with a canarypox vector prime and protein boost, attenuated poxvirus recombinants expressing HIV-1 antigens are increasingly sought as vaccine candidates against HIV/AIDS. Here we describe using systems analysis the biological and immu...

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Main Authors: Carmen Elena Gómez, Beatriz Perdiguero, Victoria Jiménez, Abdelali Filali-Mouhim, Khader Ghneim, Elias K Haddad, Esther D Quakkelaar, Julie Delaloye, Alexandre Harari, Thierry Roger, Thomas Duhen, Rafick P Sékaly, Cornelis J M Melief, Thierry Calandra, Federica Sallusto, Antonio Lanzavecchia, Ralf Wagner, Giuseppe Pantaleo, Mariano Esteban
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2012
Subjects:
Medicine
R
Science
Q
Online Access:https://doaj.org/article/d2fbd70e5f1c483eba57e0bcefc85a23
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https://doaj.org/article/d2fbd70e5f1c483eba57e0bcefc85a23

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