Directed evolution for high functional production and stability of a challenging G protein-coupled receptor
Abstract Membrane proteins such as G protein-coupled receptors (GPCRs) carry out many fundamental biological functions, are involved in a large number of physiological responses, and are thus important drug targets. To allow detailed biophysical and structural studies, most of these important recept...
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Auteurs principaux: | Yann Waltenspühl, Jeliazko R. Jeliazkov, Lutz Kummer, Andreas Plückthun |
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Format: | article |
Langue: | EN |
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Nature Portfolio
2021
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Accès en ligne: | https://doaj.org/article/d30d7a1ad5c34e6caa1d47c532bf4b8b |
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