Culture surface protein coatings affect the barrier properties and calcium signalling of hESC-RPE

Abstract Human pluripotent stem cell-derived retinal pigment epithelium (RPE) transplantation is currently under evaluation as treatment for macular degeneration. For therapeutic applications, cryostorage during cell production is typically needed with potential consequences to cell functionality. W...

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Autores principales: Taina Viheriälä, Juhana Sorvari, Teemu O. Ihalainen, Anni Mörö, Pyry Grönroos, Sabrina Schlie-Wolter, Boris Chichkov, Heli Skottman, Soile Nymark, Tanja Ilmarinen
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/d31163423f174aa6ae385f815f57c54c
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