Computational design of SARS-CoV-2 peptide binders with better predicted binding affinities than human ACE2 receptor

Abstract SARS-CoV-2 is coronavirus causing COVID-19 pandemic. To enter human cells, receptor binding domain of S1 subunit of SARS-CoV-2 (SARS-CoV-2-RBD) binds to peptidase domain (PD) of angiotensin-converting enzyme 2 (ACE2) receptor. Employing peptides to inhibit binding between SARS-CoV-2-RBD and...

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Autores principales: Thassanai Sitthiyotha, Surasak Chunsrivirot
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/d32c88726a6b4ff48b66bc613ee2b969
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