Tumor-reprogrammed resident T cells resist radiation to control tumors
Lymphocytes are considered one of the most radiosensitive cell types in the body. Here the authors show that unlike circulating lymphocytes, tumor-infiltrating T cells survive therapeutic doses of irradiation, remaining functional and contributing to radiotherapy induced anti-tumor immunity.
Guardado en:
Autores principales: | Ainhoa Arina, Michael Beckett, Christian Fernandez, Wenxin Zheng, Sean Pitroda, Steven J. Chmura, Jason J. Luke, Martin Forde, Yuzhu Hou, Byron Burnette, Helena Mauceri, Israel Lowy, Tasha Sims, Nikolai Khodarev, Yang-Xin Fu, Ralph R. Weichselbaum |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2019
|
Materias: | |
Acceso en línea: | https://doaj.org/article/d33bd7c45d314883a3946267882043c5 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Recent Metabolomics Analysis in Tumor Metabolism Reprogramming
por: Jingjing Han, et al.
Publicado: (2021) -
Metabolic Reprogramming in the Tumor Microenvironment With Immunocytes and Immune Checkpoints
por: Yaolin Xu, et al.
Publicado: (2021) -
Mimicking the Endometrial Cancer Tumor Microenvironment to Reprogram Tumor-Associated Macrophages in Disintegrable Supramolecular Gelatin Hydrogel
por: Huang Y, et al.
Publicado: (2020) -
Host STING-dependent MDSC mobilization drives extrinsic radiation resistance
por: Hua Liang, et al.
Publicado: (2017) -
Immunostimulatory nanomedicines synergize with checkpoint blockade immunotherapy to eradicate colorectal tumors
por: Xiaopin Duan, et al.
Publicado: (2019)