EZH2 presents a therapeutic target for neuroendocrine tumors of the small intestine

Abstract Small intestinal neuroendocrine tumors (SI-NETs) are slow-growing tumors that seem genetically quite stable without highly recurrent mutations, but are epigenetically dysregulated. In contrast to the undetectable expression of the enhancer of zeste homolog 2 (EZH2) histone methyltransferase...

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Autores principales: Elham Barazeghi, Per Hellman, Olov Norlén, Gunnar Westin, Peter Stålberg
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/d351b9e2cae3458c9b1d12c37c08e7b8
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