The Heparanase Inhibitor (Sulodexide) Decreases Urine Glycosaminoglycan Excretion and Mitigates Functional and Histological Renal Damages in Diabetic Rats
Background/objectives: Recent data suggest a role for heparanase in several proteinuric conditions. An increased glomerular heparanase expression is associated with loss of heparan sulfate in the glomerular basement membrane (GBM). The aim of the present study was to investigate the renal effects of...
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| Auteurs principaux: | , , |
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| Format: | article |
| Langue: | EN |
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Sciendo
2019
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| Accès en ligne: | https://doaj.org/article/d37568e71c8444bbbb5bf2c8fc19d5ec |
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