The Heparanase Inhibitor (Sulodexide) Decreases Urine Glycosaminoglycan Excretion and Mitigates Functional and Histological Renal Damages in Diabetic Rats

Background/objectives: Recent data suggest a role for heparanase in several proteinuric conditions. An increased glomerular heparanase expression is associated with loss of heparan sulfate in the glomerular basement membrane (GBM). The aim of the present study was to investigate the renal effects of...

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Autores principales: Roshan-Milani S., Khalilpour J., Fard A. Abdollahzade
Formato: article
Lenguaje:EN
Publicado: Sciendo 2019
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R
Acceso en línea:https://doaj.org/article/d37568e71c8444bbbb5bf2c8fc19d5ec
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