The Heparanase Inhibitor (Sulodexide) Decreases Urine Glycosaminoglycan Excretion and Mitigates Functional and Histological Renal Damages in Diabetic Rats

Background/objectives: Recent data suggest a role for heparanase in several proteinuric conditions. An increased glomerular heparanase expression is associated with loss of heparan sulfate in the glomerular basement membrane (GBM). The aim of the present study was to investigate the renal effects of...

Full description

Saved in:
Bibliographic Details
Main Authors: Roshan-Milani S., Khalilpour J., Fard A. Abdollahzade
Format: article
Language:EN
Published: Sciendo 2019
Subjects:
R
Online Access:https://doaj.org/article/d37568e71c8444bbbb5bf2c8fc19d5ec
Tags: Add Tag
No Tags, Be the first to tag this record!