Predicting the Reliability of Drug-target Interaction Predictions with Maximum Coverage of Target Space

Abstract Many computational methods to predict the macromolecular targets of small organic molecules have been presented to date. Despite progress, target prediction methods still have important limitations. For example, the most accurate methods implicitly restrict their predictions to a relatively...

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Auteurs principaux: Antonio Peón, Stefan Naulaerts, Pedro J. Ballester
Format: article
Langue:EN
Publié: Nature Portfolio 2017
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Accès en ligne:https://doaj.org/article/d3c61d3ca21340c9835c42f70e3c47ad
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