Binding mode analyses and pharmacophore model development for stilbene derivatives as a novel and competitive class of α-glucosidase inhibitors.

Stilbene urea derivatives as a novel and competitive class of non-glycosidic α-glucosidase inhibitors are effective for the treatment of type II diabetes and obesity. The main purposes of our molecular modeling study are to explore the most suitable binding poses of stilbene derivatives with analyzi...

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Main Authors: Yuno Lee, Songmi Kim, Jun Young Kim, Mahreen Arooj, Siu Kim, Swan Hwang, Byeong-Woo Kim, Ki Hun Park, Keun Woo Lee
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2014
Subjects:
R
Q
Online Access:https://doaj.org/article/d3ce32c651c1477a9d8cc4227adf0de6
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