Binding mode analyses and pharmacophore model development for stilbene derivatives as a novel and competitive class of α-glucosidase inhibitors.
Stilbene urea derivatives as a novel and competitive class of non-glycosidic α-glucosidase inhibitors are effective for the treatment of type II diabetes and obesity. The main purposes of our molecular modeling study are to explore the most suitable binding poses of stilbene derivatives with analyzi...
Saved in:
Main Authors: | Yuno Lee, Songmi Kim, Jun Young Kim, Mahreen Arooj, Siu Kim, Swan Hwang, Byeong-Woo Kim, Ki Hun Park, Keun Woo Lee |
---|---|
Format: | article |
Language: | EN |
Published: |
Public Library of Science (PLoS)
2014
|
Subjects: | |
Online Access: | https://doaj.org/article/d3ce32c651c1477a9d8cc4227adf0de6 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
- Pharmacophore
-
Exploration of virtual candidates for human HMG-CoA reductase inhibitors using pharmacophore modeling and molecular dynamics simulations.
by: Minky Son, et al.
Published: (2013) -
Spectrum of antibacterial activity and mode of action of a novel tris-stilbene bacteriostatic compound
by: Nikki Y. T. Man, et al.
Published: (2018) -
Protein conformational transitions explored by a morphing approach based on normal mode analysis in internal coordinates.
by: Byung Ho Lee, et al.
Published: (2021) -
Protein conformational transitions explored by a morphing approach based on normal mode analysis in internal coordinates
by: Byung Ho Lee, et al.
Published: (2021)