Pontin arginine methylation by CARM1 is crucial for epigenetic regulation of autophagy

Epigenetic regulations of autophagy have emerged as mechanisms for maintaining cellular homeostasis. Here the authors reveal that the CARM1-Pontin-FOXO3a signaling axis can activate autophagy related genes through enhancer activation.

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Young Suk Yu, Hijai R. Shin, Dongha Kim, Seon Ah Baek, Seon Ah Choi, Hyejin Ahn, Amen Shamim, Jeonghwan Kim, Ik Soo Kim, Kyeong Kyu Kim, Kyoung-Jae Won, Sung Hee Baek
Format: article
Langue:EN
Publié: Nature Portfolio 2020
Sujets:
Q
Accès en ligne:https://doaj.org/article/d3d05dcdba32445ea71f99c03fc33bd9
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!