Pontin arginine methylation by CARM1 is crucial for epigenetic regulation of autophagy

Epigenetic regulations of autophagy have emerged as mechanisms for maintaining cellular homeostasis. Here the authors reveal that the CARM1-Pontin-FOXO3a signaling axis can activate autophagy related genes through enhancer activation.

Guardado en:
Detalles Bibliográficos
Autores principales: Young Suk Yu, Hijai R. Shin, Dongha Kim, Seon Ah Baek, Seon Ah Choi, Hyejin Ahn, Amen Shamim, Jeonghwan Kim, Ik Soo Kim, Kyeong Kyu Kim, Kyoung-Jae Won, Sung Hee Baek
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
Materias:
Q
Acceso en línea:https://doaj.org/article/d3d05dcdba32445ea71f99c03fc33bd9
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
id oai:doaj.org-article:d3d05dcdba32445ea71f99c03fc33bd9
record_format dspace
spelling oai:doaj.org-article:d3d05dcdba32445ea71f99c03fc33bd92021-12-02T13:23:48ZPontin arginine methylation by CARM1 is crucial for epigenetic regulation of autophagy10.1038/s41467-020-20080-92041-1723https://doaj.org/article/d3d05dcdba32445ea71f99c03fc33bd92020-12-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-20080-9https://doaj.org/toc/2041-1723Epigenetic regulations of autophagy have emerged as mechanisms for maintaining cellular homeostasis. Here the authors reveal that the CARM1-Pontin-FOXO3a signaling axis can activate autophagy related genes through enhancer activation.Young Suk YuHijai R. ShinDongha KimSeon Ah BaekSeon Ah ChoiHyejin AhnAmen ShamimJeonghwan KimIk Soo KimKyeong Kyu KimKyoung-Jae WonSung Hee BaekNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-18 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Young Suk Yu
Hijai R. Shin
Dongha Kim
Seon Ah Baek
Seon Ah Choi
Hyejin Ahn
Amen Shamim
Jeonghwan Kim
Ik Soo Kim
Kyeong Kyu Kim
Kyoung-Jae Won
Sung Hee Baek
Pontin arginine methylation by CARM1 is crucial for epigenetic regulation of autophagy
description Epigenetic regulations of autophagy have emerged as mechanisms for maintaining cellular homeostasis. Here the authors reveal that the CARM1-Pontin-FOXO3a signaling axis can activate autophagy related genes through enhancer activation.
format article
author Young Suk Yu
Hijai R. Shin
Dongha Kim
Seon Ah Baek
Seon Ah Choi
Hyejin Ahn
Amen Shamim
Jeonghwan Kim
Ik Soo Kim
Kyeong Kyu Kim
Kyoung-Jae Won
Sung Hee Baek
author_facet Young Suk Yu
Hijai R. Shin
Dongha Kim
Seon Ah Baek
Seon Ah Choi
Hyejin Ahn
Amen Shamim
Jeonghwan Kim
Ik Soo Kim
Kyeong Kyu Kim
Kyoung-Jae Won
Sung Hee Baek
author_sort Young Suk Yu
title Pontin arginine methylation by CARM1 is crucial for epigenetic regulation of autophagy
title_short Pontin arginine methylation by CARM1 is crucial for epigenetic regulation of autophagy
title_full Pontin arginine methylation by CARM1 is crucial for epigenetic regulation of autophagy
title_fullStr Pontin arginine methylation by CARM1 is crucial for epigenetic regulation of autophagy
title_full_unstemmed Pontin arginine methylation by CARM1 is crucial for epigenetic regulation of autophagy
title_sort pontin arginine methylation by carm1 is crucial for epigenetic regulation of autophagy
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/d3d05dcdba32445ea71f99c03fc33bd9
work_keys_str_mv AT youngsukyu pontinargininemethylationbycarm1iscrucialforepigeneticregulationofautophagy
AT hijairshin pontinargininemethylationbycarm1iscrucialforepigeneticregulationofautophagy
AT donghakim pontinargininemethylationbycarm1iscrucialforepigeneticregulationofautophagy
AT seonahbaek pontinargininemethylationbycarm1iscrucialforepigeneticregulationofautophagy
AT seonahchoi pontinargininemethylationbycarm1iscrucialforepigeneticregulationofautophagy
AT hyejinahn pontinargininemethylationbycarm1iscrucialforepigeneticregulationofautophagy
AT amenshamim pontinargininemethylationbycarm1iscrucialforepigeneticregulationofautophagy
AT jeonghwankim pontinargininemethylationbycarm1iscrucialforepigeneticregulationofautophagy
AT iksookim pontinargininemethylationbycarm1iscrucialforepigeneticregulationofautophagy
AT kyeongkyukim pontinargininemethylationbycarm1iscrucialforepigeneticregulationofautophagy
AT kyoungjaewon pontinargininemethylationbycarm1iscrucialforepigeneticregulationofautophagy
AT sungheebaek pontinargininemethylationbycarm1iscrucialforepigeneticregulationofautophagy
_version_ 1718393182149935104