Pontin arginine methylation by CARM1 is crucial for epigenetic regulation of autophagy
Epigenetic regulations of autophagy have emerged as mechanisms for maintaining cellular homeostasis. Here the authors reveal that the CARM1-Pontin-FOXO3a signaling axis can activate autophagy related genes through enhancer activation.
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Nature Portfolio
2020
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oai:doaj.org-article:d3d05dcdba32445ea71f99c03fc33bd92021-12-02T13:23:48ZPontin arginine methylation by CARM1 is crucial for epigenetic regulation of autophagy10.1038/s41467-020-20080-92041-1723https://doaj.org/article/d3d05dcdba32445ea71f99c03fc33bd92020-12-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-20080-9https://doaj.org/toc/2041-1723Epigenetic regulations of autophagy have emerged as mechanisms for maintaining cellular homeostasis. Here the authors reveal that the CARM1-Pontin-FOXO3a signaling axis can activate autophagy related genes through enhancer activation.Young Suk YuHijai R. ShinDongha KimSeon Ah BaekSeon Ah ChoiHyejin AhnAmen ShamimJeonghwan KimIk Soo KimKyeong Kyu KimKyoung-Jae WonSung Hee BaekNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-18 (2020) |
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Science Q Young Suk Yu Hijai R. Shin Dongha Kim Seon Ah Baek Seon Ah Choi Hyejin Ahn Amen Shamim Jeonghwan Kim Ik Soo Kim Kyeong Kyu Kim Kyoung-Jae Won Sung Hee Baek Pontin arginine methylation by CARM1 is crucial for epigenetic regulation of autophagy |
description |
Epigenetic regulations of autophagy have emerged as mechanisms for maintaining cellular homeostasis. Here the authors reveal that the CARM1-Pontin-FOXO3a signaling axis can activate autophagy related genes through enhancer activation. |
format |
article |
author |
Young Suk Yu Hijai R. Shin Dongha Kim Seon Ah Baek Seon Ah Choi Hyejin Ahn Amen Shamim Jeonghwan Kim Ik Soo Kim Kyeong Kyu Kim Kyoung-Jae Won Sung Hee Baek |
author_facet |
Young Suk Yu Hijai R. Shin Dongha Kim Seon Ah Baek Seon Ah Choi Hyejin Ahn Amen Shamim Jeonghwan Kim Ik Soo Kim Kyeong Kyu Kim Kyoung-Jae Won Sung Hee Baek |
author_sort |
Young Suk Yu |
title |
Pontin arginine methylation by CARM1 is crucial for epigenetic regulation of autophagy |
title_short |
Pontin arginine methylation by CARM1 is crucial for epigenetic regulation of autophagy |
title_full |
Pontin arginine methylation by CARM1 is crucial for epigenetic regulation of autophagy |
title_fullStr |
Pontin arginine methylation by CARM1 is crucial for epigenetic regulation of autophagy |
title_full_unstemmed |
Pontin arginine methylation by CARM1 is crucial for epigenetic regulation of autophagy |
title_sort |
pontin arginine methylation by carm1 is crucial for epigenetic regulation of autophagy |
publisher |
Nature Portfolio |
publishDate |
2020 |
url |
https://doaj.org/article/d3d05dcdba32445ea71f99c03fc33bd9 |
work_keys_str_mv |
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1718393182149935104 |