Shared active site architecture between archaeal PolD and multi-subunit RNA polymerases revealed by X-ray crystallography

The structures of many DNA polymerases is known, but PolD was a missing piece. Here, the authors report the crystal structure of this protein and use it to connect the DNA replication machinery with the transcription machinery in the same protein family.

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Autores principales: Ludovic Sauguet, Pierre Raia, Ghislaine Henneke, Marc Delarue
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
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Acceso en línea:https://doaj.org/article/d4208d3f70564e7cb7b842ba3ac7b8a7
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