Loss of MAX results in meiotic entry in mouse embryonic and germline stem cells

The mechanisms that trigger meiosis in germ cells and halt this process in non-germline cells are unclear. Here, the authors show that knockout of Maxin embryonic stem cells results in meiotic onset in a mechanism that involves the PRC1 complex.

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Autores principales:	Ayumu Suzuki, Masataka Hirasaki, Tomoaki Hishida, Jun Wu, Daiji Okamura, Atsushi Ueda, Masazumi Nishimoto, Yutaka Nakachi, Yosuke Mizuno, Yasushi Okazaki, Yasuhisa Matsui, Juan Carlos Izpisua Belmonte, Akihiko Okuda
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/d48b7e92a9494f59a69114f0d697881b
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spelling	oai:doaj.org-article:d48b7e92a9494f59a69114f0d697881b2021-12-02T14:40:13ZLoss of MAX results in meiotic entry in mouse embryonic and germline stem cells10.1038/ncomms110562041-1723https://doaj.org/article/d48b7e92a9494f59a69114f0d697881b2016-03-01T00:00:00Zhttps://doi.org/10.1038/ncomms11056https://doaj.org/toc/2041-1723The mechanisms that trigger meiosis in germ cells and halt this process in non-germline cells are unclear. Here, the authors show that knockout of Maxin embryonic stem cells results in meiotic onset in a mechanism that involves the PRC1 complex.Ayumu SuzukiMasataka HirasakiTomoaki HishidaJun WuDaiji OkamuraAtsushi UedaMasazumi NishimotoYutaka NakachiYosuke MizunoYasushi OkazakiYasuhisa MatsuiJuan Carlos Izpisua BelmonteAkihiko OkudaNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-15 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Ayumu Suzuki Masataka Hirasaki Tomoaki Hishida Jun Wu Daiji Okamura Atsushi Ueda Masazumi Nishimoto Yutaka Nakachi Yosuke Mizuno Yasushi Okazaki Yasuhisa Matsui Juan Carlos Izpisua Belmonte Akihiko Okuda Loss of MAX results in meiotic entry in mouse embryonic and germline stem cells
description	The mechanisms that trigger meiosis in germ cells and halt this process in non-germline cells are unclear. Here, the authors show that knockout of Maxin embryonic stem cells results in meiotic onset in a mechanism that involves the PRC1 complex.
format	article
author	Ayumu Suzuki Masataka Hirasaki Tomoaki Hishida Jun Wu Daiji Okamura Atsushi Ueda Masazumi Nishimoto Yutaka Nakachi Yosuke Mizuno Yasushi Okazaki Yasuhisa Matsui Juan Carlos Izpisua Belmonte Akihiko Okuda
author_facet	Ayumu Suzuki Masataka Hirasaki Tomoaki Hishida Jun Wu Daiji Okamura Atsushi Ueda Masazumi Nishimoto Yutaka Nakachi Yosuke Mizuno Yasushi Okazaki Yasuhisa Matsui Juan Carlos Izpisua Belmonte Akihiko Okuda
author_sort	Ayumu Suzuki
title	Loss of MAX results in meiotic entry in mouse embryonic and germline stem cells
title_short	Loss of MAX results in meiotic entry in mouse embryonic and germline stem cells
title_full	Loss of MAX results in meiotic entry in mouse embryonic and germline stem cells
title_fullStr	Loss of MAX results in meiotic entry in mouse embryonic and germline stem cells
title_full_unstemmed	Loss of MAX results in meiotic entry in mouse embryonic and germline stem cells
title_sort	loss of max results in meiotic entry in mouse embryonic and germline stem cells
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/d48b7e92a9494f59a69114f0d697881b
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Loss of MAX results in meiotic entry in mouse embryonic and germline stem cells

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