RNA-seq and GSEA identifies suppression of ligand-gated chloride efflux channels as the major gene pathway contributing to form deprivation myopia

Abstract Currently there is no consensus regarding the aetiology of the excessive ocular volume that characterizes high myopia. Thus, we aimed to test whether the gene pathways identified by gene set enrichment analysis of RNA-seq transcriptomics refutes the predictions of the Retinal Ion Driven Eff...

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Autores principales: Loretta Giummarra Vocale, Sheila Crewther, Nina Riddell, Nathan E. Hall, Melanie Murphy, David Crewther
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/d4a0d9fdf0174c559e718bd7915cc529
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