The GSK3 signaling pathway is activated by cocaine and is critical for cocaine conditioned reward in mice.

The Akt - GSK3 signaling pathway has been recently implicated in psychostimulant-induced behavioral and cellular effects. Here, the ability of cocaine to regulate the activity of Akt and GSK3 was investigated by measuring the phosphorylation states of the two kinases. The anatomical specificity of t...

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Auteurs principaux: Jonathan S Miller, Jeffrey L Barr, Lauren J Harper, Rachel L Poole, Thomas J Gould, Ellen M Unterwald
Format: article
Langue:EN
Publié: Public Library of Science (PLoS) 2014
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Accès en ligne:https://doaj.org/article/d4b567fb87404a50bc2ad13d8c19f62b
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