Discovery of new TLR7 agonists by a combination of statistical learning-based QSAR, virtual screening, and molecular dynamics
Search for new antiviral medications has surged in the past two years due to the COVID-19 crisis. Toll-like receptor 7 (TLR7) is among one of the most important TLR proteins of innate immunity that is responsible for broad antiviral response and immune system control. TLR7 agonists, as both vaccine...
Guardado en:
Autores principales: | Ardavan Abiri, Masoud Rezaei, Mohammad Hossein Zeighami, Younes Vaezpour, Leili Dehghan, Maedeh KhorramGhahfarokhi |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://doaj.org/article/d4b8ad598b8a4ec79183a44ac3cc0543 |
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