Hydrophobic Optimization of Functional Poly(TPAE-co-suberoyl chloride) for Extrahepatic mRNA Delivery following Intravenous Administration
Messenger RNA (mRNA) has generated great attention due to its broad potential therapeutic applications, including vaccines, protein replacement therapy, and immunotherapy. Compared to other nucleic acids (e.g., siRNA and pDNA), there are more opportunities to improve the delivery efficacy of mRNA th...
Enregistré dans:
Auteurs principaux: | Xueliang Yu, Shuai Liu, Qiang Cheng, Sang M. Lee, Tuo Wei, Di Zhang, Lukas Farbiak, Lindsay T. Johnson, Xu Wang, Daniel John Siegwart |
---|---|
Format: | article |
Langue: | EN |
Publié: |
MDPI AG
2021
|
Sujets: | |
Accès en ligne: | https://doaj.org/article/d4c84e7de6404a5fad7c36abe82adb46 |
Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|
Documents similaires
-
Efficient Messenger RNA Delivery to the Kidney Using Renal Pelvis Injection in Mice
par: Natsuko Oyama, et autres
Publié: (2021) -
mRNA Degradation Rates Are Coupled to Metabolic Status in <named-content content-type="genus-species">Mycobacterium smegmatis</named-content>
par: Diego A. Vargas-Blanco, et autres
Publié: (2019) -
Translational Regulation Promotes Oxidative Stress Resistance in the Human Fungal Pathogen <named-content content-type="genus-species">Cryptococcus neoformans</named-content>
par: Jay Leipheimer, et autres
Publié: (2019) -
Expression of the carotenoid biosynthesis genes in Xanthophyllomyces dendrorhous
par: LODATO,P, et autres
Publié: (2007) -
Changes in PEP Carboxylase, Rubisco and Rubisco activase mRNA levels from maize (Zea mays) exposed to a chronic ozone stress
par: LEITAO,LOUIS, et autres
Publié: (2007)