Functionally Overlapping Variants Control Tuberculosis Susceptibility in Collaborative Cross Mice

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Functionally Overlapping Variants Control Tuberculosis Susceptibility in Collaborative Cross Mice

ABSTRACT Host genetics plays an important role in determining the outcome of Mycobacterium tuberculosis infection. We previously found that Collaborative Cross (CC) mouse strains differ in their susceptibility to M. tuberculosis and that the CC042/GeniUnc (CC042) strain suffered from a rapidly progr...

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Autores principales:	Clare M. Smith, Megan K. Proulx, Rocky Lai, Michael C. Kiritsy, Timothy A. Bell, Pablo Hock, Fernando Pardo-Manuel de Villena, Martin T. Ferris, Richard E. Baker, Samuel M. Behar, Christopher M. Sassetti
Formato:	article
Lenguaje:	EN
Publicado:	American Society for Microbiology 2019
Materias:	Mycobacterium tuberculosis adaptive immunity Collaborative Cross mice host genetics host response host-pathogen interactions Microbiology QR1-502
Acceso en línea:	https://doaj.org/article/d4cab79506754b9ea4ff592ecc872668
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

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