Exosome-delivered EGFR regulates liver microenvironment to promote gastric cancer liver metastasis

EGFR signalling has been linked to cancer development but whether it has any role in pre-metastatic niche formation is not known. Here the authors show that gastric cancer cells send EGFR through exosomes to the liver where it causes the establishment of a favourable microenvironment thus promoting...

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Autores principales: Haiyang Zhang, Ting Deng, Rui Liu, Ming Bai, Likun Zhou, Xia Wang, Shuang Li, Xinyi Wang, Haiou Yang, Jialu Li, Tao Ning, Dingzhi Huang, Hongli Li, Le Zhang, Guoguang Ying, Yi Ba
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/d4d3d21a7c36464a8fb02e163d543374
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