Biosynthesis of the nosiheptide indole side ring centers on a cryptic carrier protein NosJ

Thiopeptides such as nosiheptide are clinically-interesting antimicrobial natural products. Here the authors show the functional dissection of a series of enzymes involved in nosiheptide biosynthesis, revealing a unique biosynthetic pathway that centers on a previously-unknown carrier protein.

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Autores principales:	Wei Ding, Wenjuan Ji, Yujie Wu, Runze Wu, Wan-Qiu Liu, Tianlu Mo, Junfeng Zhao, Xiaoyan Ma, Wei Zhang, Ping Xu, Zixin Deng, Boping Tang, Yi Yu, Qi Zhang
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/d4d55f56dabb4af886a3a1b248a82e02
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spelling	oai:doaj.org-article:d4d55f56dabb4af886a3a1b248a82e022021-12-02T14:40:56ZBiosynthesis of the nosiheptide indole side ring centers on a cryptic carrier protein NosJ10.1038/s41467-017-00439-12041-1723https://doaj.org/article/d4d55f56dabb4af886a3a1b248a82e022017-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-00439-1https://doaj.org/toc/2041-1723Thiopeptides such as nosiheptide are clinically-interesting antimicrobial natural products. Here the authors show the functional dissection of a series of enzymes involved in nosiheptide biosynthesis, revealing a unique biosynthetic pathway that centers on a previously-unknown carrier protein.Wei DingWenjuan JiYujie WuRunze WuWan-Qiu LiuTianlu MoJunfeng ZhaoXiaoyan MaWei ZhangPing XuZixin DengBoping TangYi YuQi ZhangNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-7 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Wei Ding Wenjuan Ji Yujie Wu Runze Wu Wan-Qiu Liu Tianlu Mo Junfeng Zhao Xiaoyan Ma Wei Zhang Ping Xu Zixin Deng Boping Tang Yi Yu Qi Zhang Biosynthesis of the nosiheptide indole side ring centers on a cryptic carrier protein NosJ
description	Thiopeptides such as nosiheptide are clinically-interesting antimicrobial natural products. Here the authors show the functional dissection of a series of enzymes involved in nosiheptide biosynthesis, revealing a unique biosynthetic pathway that centers on a previously-unknown carrier protein.
format	article
author	Wei Ding Wenjuan Ji Yujie Wu Runze Wu Wan-Qiu Liu Tianlu Mo Junfeng Zhao Xiaoyan Ma Wei Zhang Ping Xu Zixin Deng Boping Tang Yi Yu Qi Zhang
author_facet	Wei Ding Wenjuan Ji Yujie Wu Runze Wu Wan-Qiu Liu Tianlu Mo Junfeng Zhao Xiaoyan Ma Wei Zhang Ping Xu Zixin Deng Boping Tang Yi Yu Qi Zhang
author_sort	Wei Ding
title	Biosynthesis of the nosiheptide indole side ring centers on a cryptic carrier protein NosJ
title_short	Biosynthesis of the nosiheptide indole side ring centers on a cryptic carrier protein NosJ
title_full	Biosynthesis of the nosiheptide indole side ring centers on a cryptic carrier protein NosJ
title_fullStr	Biosynthesis of the nosiheptide indole side ring centers on a cryptic carrier protein NosJ
title_full_unstemmed	Biosynthesis of the nosiheptide indole side ring centers on a cryptic carrier protein NosJ
title_sort	biosynthesis of the nosiheptide indole side ring centers on a cryptic carrier protein nosj
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/d4d55f56dabb4af886a3a1b248a82e02
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Biosynthesis of the nosiheptide indole side ring centers on a cryptic carrier protein NosJ

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