Biosynthesis of the nosiheptide indole side ring centers on a cryptic carrier protein NosJ
Thiopeptides such as nosiheptide are clinically-interesting antimicrobial natural products. Here the authors show the functional dissection of a series of enzymes involved in nosiheptide biosynthesis, revealing a unique biosynthetic pathway that centers on a previously-unknown carrier protein.
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Auteurs principaux: | , , , , , , , , , , , , , |
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Format: | article |
Langue: | EN |
Publié: |
Nature Portfolio
2017
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Accès en ligne: | https://doaj.org/article/d4d55f56dabb4af886a3a1b248a82e02 |
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