Meta-analysis of <named-content content-type="genus-species">Plasmodium falciparum</named-content> <italic toggle="yes">var</italic> Signatures Contributing to Severe Malaria in African Children and Indian Adults

Meta-analysis of <named-content content-type="genus-species">Plasmodium falciparum</named-content> <italic toggle="yes">var</italic> Signatures Contributing to Severe Malaria in African Children and Indian Adults

ABSTRACT The clinical presentation of severe Plasmodium falciparum malaria differs between children and adults, but the mechanistic basis for this remains unclear. Contributing factors to disease severity include total parasite biomass and the diverse cytoadhesive properties mediated by the polymorp...

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Auteurs principaux: Fergal Duffy, Maria Bernabeu, Prasad H. Babar, Anne Kessler, Christian W. Wang, Marina Vaz, Laura Chery, Wilson L. Mandala, Stephen J. Rogerson, Terrie E. Taylor, Karl B. Seydel, Thomas Lavstsen, Edwin Gomes, Kami Kim, John Lusingu, Pradipsinh K. Rathod, John D. Aitchison, Joseph D. Smith
Format: article
Langue:EN
Publié: American Society for Microbiology 2019
Sujets:
cerebral malaria
machine learning
malaria
PfEMP1
Plasmodium falciparum
severe malaria
Microbiology
QR1-502
Accès en ligne:https://doaj.org/article/d4ebf5cd94fa48a89e98ace612f93095
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https://doaj.org/article/d4ebf5cd94fa48a89e98ace612f93095

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