The FAD synthetase from the human pathogen Streptococcus pneumoniae: a bifunctional enzyme exhibiting activity-dependent redox requirements
Abstract Prokaryotic bifunctional FAD synthetases (FADSs) catalyze the biosynthesis of FMN and FAD, whereas in eukaryotes two enzymes are required for the same purpose. FMN and FAD are key cofactors to maintain the flavoproteome homeostasis in all type of organisms. Here we shed light to the propert...
Enregistré dans:
Auteurs principaux: | María Sebastián, Erandi Lira-Navarrete, Ana Serrano, Carlos Marcuello, Adrián Velázquez-Campoy, Anabel Lostao, Ramón Hurtado-Guerrero, Milagros Medina, Marta Martínez-Júlvez |
---|---|
Format: | article |
Langue: | EN |
Publié: |
Nature Portfolio
2017
|
Sujets: | |
Accès en ligne: | https://doaj.org/article/d4edd25e669b41d59c704c9da5d7440d |
Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|
Documents similaires
-
The trimer interface in the quaternary structure of the bifunctional prokaryotic FAD synthetase from Corynebacterium ammoniagenes
par: Ana Serrano, et autres
Publié: (2017) -
Kinetics and thermodynamics of the protein-ligand interactions in the riboflavin kinase activity of the FAD synthetase from Corynebacterium ammoniagenes
par: María Sebastián, et autres
Publié: (2017) -
Structure-Function Analysis of the Bifunctional CcsBA Heme Exporter and Cytochrome <italic toggle="yes">c</italic> Synthetase
par: Molly C. Sutherland, et autres
Publié: (2018) -
Participation of Acyl-Coenzyme A Synthetase FadD4 of Pseudomonas aeruginosa PAO1 in Acyclic Terpene/Fatty Acid Assimilation and Virulence by Lipid A Modification
par: Lorena Martínez-Alcantar, et autres
Publié: (2021) -
The role of the methyltransferase domain of bifunctional restriction enzyme RM.BpuSI in cleavage activity.
par: Arthur Sarrade-Loucheur, et autres
Publié: (2013)