BRCA2 mutations and triple-negative breast cancer.

Recently, BRCA1 germline mutations were found in a high proportion (14-34%) of patients with triple-negative breast cancer (TNBC). BRCA2 was either not analyzed or showed much lower mutation frequencies. Therefore, we screened a group of TNBC patients (n = 30) of white European descent for mutations...

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Auteurs principaux: Peter Meyer, Katharina Landgraf, Bernhard Högel, Wolfgang Eiermann, Beyhan Ataseven
Format: article
Langue:EN
Publié: Public Library of Science (PLoS) 2012
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Accès en ligne:https://doaj.org/article/d5042e952a864838ab069725a38f8820
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