Traceless native chemical ligation of lipid-modified peptide surfactants by mixed micelle formation
Sequestration of reactants in lipid vesicles is a strategy prevalent in biological systems to raise the rate and specificity of chemical reactions. Here, the authors show that micelle-assisted reactions facilitate native chemical ligation between a peptide-thioester and a Cys-peptide modified by a l...
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Autores principales: | Shuaijiang Jin, Roberto J. Brea, Andrew K. Rudd, Stuart P. Moon, Matthew R. Pratt, Neal K. Devaraj |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2020
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Materias: | |
Acceso en línea: | https://doaj.org/article/d523faaf6776431fa7a2b80e8cddfeb5 |
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