A new type of DNA phosphorothioation-based antiviral system in archaea

The prokaryote defence system Dnd relies on phosphorothioation (PT) of DNA backbone to distinguish between self and non-self DNA. Here, Xiong et al. describe a previously uncharacterized PT-based antiviral system that is independent of the canonical Dnd and is widespread in Archaea and Bacteria.

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Autores principales:	Lei Xiong, Siyi Liu, Si Chen, Yao Xiao, Bochen Zhu, Yali Gao, Yujing Zhang, Beibei Chen, Jie Luo, Zixin Deng, Xiangdong Chen, Lianrong Wang, Shi Chen
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/d5520ef95b4f42e68fb602a3ec748976
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spelling	oai:doaj.org-article:d5520ef95b4f42e68fb602a3ec7489762021-12-02T16:58:16ZA new type of DNA phosphorothioation-based antiviral system in archaea10.1038/s41467-019-09390-92041-1723https://doaj.org/article/d5520ef95b4f42e68fb602a3ec7489762019-04-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-09390-9https://doaj.org/toc/2041-1723The prokaryote defence system Dnd relies on phosphorothioation (PT) of DNA backbone to distinguish between self and non-self DNA. Here, Xiong et al. describe a previously uncharacterized PT-based antiviral system that is independent of the canonical Dnd and is widespread in Archaea and Bacteria.Lei XiongSiyi LiuSi ChenYao XiaoBochen ZhuYali GaoYujing ZhangBeibei ChenJie LuoZixin DengXiangdong ChenLianrong WangShi ChenNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Lei Xiong Siyi Liu Si Chen Yao Xiao Bochen Zhu Yali Gao Yujing Zhang Beibei Chen Jie Luo Zixin Deng Xiangdong Chen Lianrong Wang Shi Chen A new type of DNA phosphorothioation-based antiviral system in archaea
description	The prokaryote defence system Dnd relies on phosphorothioation (PT) of DNA backbone to distinguish between self and non-self DNA. Here, Xiong et al. describe a previously uncharacterized PT-based antiviral system that is independent of the canonical Dnd and is widespread in Archaea and Bacteria.
format	article
author	Lei Xiong Siyi Liu Si Chen Yao Xiao Bochen Zhu Yali Gao Yujing Zhang Beibei Chen Jie Luo Zixin Deng Xiangdong Chen Lianrong Wang Shi Chen
author_facet	Lei Xiong Siyi Liu Si Chen Yao Xiao Bochen Zhu Yali Gao Yujing Zhang Beibei Chen Jie Luo Zixin Deng Xiangdong Chen Lianrong Wang Shi Chen
author_sort	Lei Xiong
title	A new type of DNA phosphorothioation-based antiviral system in archaea
title_short	A new type of DNA phosphorothioation-based antiviral system in archaea
title_full	A new type of DNA phosphorothioation-based antiviral system in archaea
title_fullStr	A new type of DNA phosphorothioation-based antiviral system in archaea
title_full_unstemmed	A new type of DNA phosphorothioation-based antiviral system in archaea
title_sort	new type of dna phosphorothioation-based antiviral system in archaea
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/d5520ef95b4f42e68fb602a3ec748976
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A new type of DNA phosphorothioation-based antiviral system in archaea

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