A genetically encoded anti-CRISPR protein constrains gene drive spread and prevents population suppression

Technologies that can halt the spread of gene drives would be highly useful in controlling or reverting their effect. Here the authors use the anti-CRISPR protein AcrIIA4 to inactivate drives in A. gambiae.

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Autores principales: Chrysanthi Taxiarchi, Andrea Beaghton, Nayomi Illansinhage Don, Kyros Kyrou, Matthew Gribble, Dammy Shittu, Scott P. Collins, Chase L. Beisel, Roberto Galizi, Andrea Crisanti
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/d5874a5ae9a2467ba0f3206162213461
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spelling oai:doaj.org-article:d5874a5ae9a2467ba0f32061622134612021-12-02T17:45:09ZA genetically encoded anti-CRISPR protein constrains gene drive spread and prevents population suppression10.1038/s41467-021-24214-52041-1723https://doaj.org/article/d5874a5ae9a2467ba0f32061622134612021-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-24214-5https://doaj.org/toc/2041-1723Technologies that can halt the spread of gene drives would be highly useful in controlling or reverting their effect. Here the authors use the anti-CRISPR protein AcrIIA4 to inactivate drives in A. gambiae.Chrysanthi TaxiarchiAndrea BeaghtonNayomi Illansinhage DonKyros KyrouMatthew GribbleDammy ShittuScott P. CollinsChase L. BeiselRoberto GaliziAndrea CrisantiNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-8 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Chrysanthi Taxiarchi
Andrea Beaghton
Nayomi Illansinhage Don
Kyros Kyrou
Matthew Gribble
Dammy Shittu
Scott P. Collins
Chase L. Beisel
Roberto Galizi
Andrea Crisanti
A genetically encoded anti-CRISPR protein constrains gene drive spread and prevents population suppression
description Technologies that can halt the spread of gene drives would be highly useful in controlling or reverting their effect. Here the authors use the anti-CRISPR protein AcrIIA4 to inactivate drives in A. gambiae.
format article
author Chrysanthi Taxiarchi
Andrea Beaghton
Nayomi Illansinhage Don
Kyros Kyrou
Matthew Gribble
Dammy Shittu
Scott P. Collins
Chase L. Beisel
Roberto Galizi
Andrea Crisanti
author_facet Chrysanthi Taxiarchi
Andrea Beaghton
Nayomi Illansinhage Don
Kyros Kyrou
Matthew Gribble
Dammy Shittu
Scott P. Collins
Chase L. Beisel
Roberto Galizi
Andrea Crisanti
author_sort Chrysanthi Taxiarchi
title A genetically encoded anti-CRISPR protein constrains gene drive spread and prevents population suppression
title_short A genetically encoded anti-CRISPR protein constrains gene drive spread and prevents population suppression
title_full A genetically encoded anti-CRISPR protein constrains gene drive spread and prevents population suppression
title_fullStr A genetically encoded anti-CRISPR protein constrains gene drive spread and prevents population suppression
title_full_unstemmed A genetically encoded anti-CRISPR protein constrains gene drive spread and prevents population suppression
title_sort genetically encoded anti-crispr protein constrains gene drive spread and prevents population suppression
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/d5874a5ae9a2467ba0f3206162213461
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