A genetically encoded anti-CRISPR protein constrains gene drive spread and prevents population suppression
Technologies that can halt the spread of gene drives would be highly useful in controlling or reverting their effect. Here the authors use the anti-CRISPR protein AcrIIA4 to inactivate drives in A. gambiae.
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Nature Portfolio
2021
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oai:doaj.org-article:d5874a5ae9a2467ba0f32061622134612021-12-02T17:45:09ZA genetically encoded anti-CRISPR protein constrains gene drive spread and prevents population suppression10.1038/s41467-021-24214-52041-1723https://doaj.org/article/d5874a5ae9a2467ba0f32061622134612021-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-24214-5https://doaj.org/toc/2041-1723Technologies that can halt the spread of gene drives would be highly useful in controlling or reverting their effect. Here the authors use the anti-CRISPR protein AcrIIA4 to inactivate drives in A. gambiae.Chrysanthi TaxiarchiAndrea BeaghtonNayomi Illansinhage DonKyros KyrouMatthew GribbleDammy ShittuScott P. CollinsChase L. BeiselRoberto GaliziAndrea CrisantiNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-8 (2021) |
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Science Q Chrysanthi Taxiarchi Andrea Beaghton Nayomi Illansinhage Don Kyros Kyrou Matthew Gribble Dammy Shittu Scott P. Collins Chase L. Beisel Roberto Galizi Andrea Crisanti A genetically encoded anti-CRISPR protein constrains gene drive spread and prevents population suppression |
description |
Technologies that can halt the spread of gene drives would be highly useful in controlling or reverting their effect. Here the authors use the anti-CRISPR protein AcrIIA4 to inactivate drives in A. gambiae. |
format |
article |
author |
Chrysanthi Taxiarchi Andrea Beaghton Nayomi Illansinhage Don Kyros Kyrou Matthew Gribble Dammy Shittu Scott P. Collins Chase L. Beisel Roberto Galizi Andrea Crisanti |
author_facet |
Chrysanthi Taxiarchi Andrea Beaghton Nayomi Illansinhage Don Kyros Kyrou Matthew Gribble Dammy Shittu Scott P. Collins Chase L. Beisel Roberto Galizi Andrea Crisanti |
author_sort |
Chrysanthi Taxiarchi |
title |
A genetically encoded anti-CRISPR protein constrains gene drive spread and prevents population suppression |
title_short |
A genetically encoded anti-CRISPR protein constrains gene drive spread and prevents population suppression |
title_full |
A genetically encoded anti-CRISPR protein constrains gene drive spread and prevents population suppression |
title_fullStr |
A genetically encoded anti-CRISPR protein constrains gene drive spread and prevents population suppression |
title_full_unstemmed |
A genetically encoded anti-CRISPR protein constrains gene drive spread and prevents population suppression |
title_sort |
genetically encoded anti-crispr protein constrains gene drive spread and prevents population suppression |
publisher |
Nature Portfolio |
publishDate |
2021 |
url |
https://doaj.org/article/d5874a5ae9a2467ba0f3206162213461 |
work_keys_str_mv |
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1718379615498534912 |