Complement factor H protects tumor cell-derived exosomes from complement-dependent lysis and phagocytosis.

Exosomes are a class of extracellular vesicles (EVs) that are mediators of normal intercellular communication, but exosomes are also used by tumor cells to promote oncogenesis and metastasis. Complement factor H (CFH) protects host cells from attack and destruction by the alternative pathway of comp...

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Autores principales: Ryan T Bushey, Elizabeth B Gottlin, Michael J Campa, Edward F Patz
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2021
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Acceso en línea:https://doaj.org/article/d597752f28b949a08bce0754a7d74de1
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