Complement factor H protects tumor cell-derived exosomes from complement-dependent lysis and phagocytosis.
Exosomes are a class of extracellular vesicles (EVs) that are mediators of normal intercellular communication, but exosomes are also used by tumor cells to promote oncogenesis and metastasis. Complement factor H (CFH) protects host cells from attack and destruction by the alternative pathway of comp...
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Autores principales: | , , , |
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Formato: | article |
Lenguaje: | EN |
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Public Library of Science (PLoS)
2021
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Acceso en línea: | https://doaj.org/article/d597752f28b949a08bce0754a7d74de1 |
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