Random-PE: an efficient integration of random sequences into mammalian genome by prime editing
Abstract Prime editing (PE) enables efficiently targeted introduction of multiple types of small-sized genetic change without requiring double-strand breaks or donor templates. Here we designed a simple strategy to introduce random DNA sequences into targeted genomic loci by prime editing, which we...
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| Auteurs principaux: | , , , , , , , |
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| Format: | article |
| Langue: | EN |
| Publié: |
Springer
2021
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| Sujets: | |
| Accès en ligne: | https://doaj.org/article/d5b86a6e19364c48be43fc0880890585 |
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