Impact of DNA methylation on 3D genome structure

Multi-layered epigenetic regulation in higher eukaryotes makes it challenging to disentangle the individual effects of modifications on chromatin structure and function. Here, the authors expressed mammalian DNA methyltransferases in yeast, which have no DNA methylation, to show that methylation has...

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Autores principales:	Diana Buitrago, Mireia Labrador, Juan Pablo Arcon, Rafael Lema, Oscar Flores, Anna Esteve-Codina, Julie Blanc, Nuria Villegas, David Bellido, Marta Gut, Pablo D. Dans, Simon C. Heath, Ivo G. Gut, Isabelle Brun Heath, Modesto Orozco
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/d5ee7c9961b041b8a4708bc652b9e485
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spelling	oai:doaj.org-article:d5ee7c9961b041b8a4708bc652b9e4852021-12-02T16:52:58ZImpact of DNA methylation on 3D genome structure10.1038/s41467-021-23142-82041-1723https://doaj.org/article/d5ee7c9961b041b8a4708bc652b9e4852021-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-23142-8https://doaj.org/toc/2041-1723Multi-layered epigenetic regulation in higher eukaryotes makes it challenging to disentangle the individual effects of modifications on chromatin structure and function. Here, the authors expressed mammalian DNA methyltransferases in yeast, which have no DNA methylation, to show that methylation has intrinsic effects on chromatin structure.Diana BuitragoMireia LabradorJuan Pablo ArconRafael LemaOscar FloresAnna Esteve-CodinaJulie BlancNuria VillegasDavid BellidoMarta GutPablo D. DansSimon C. HeathIvo G. GutIsabelle Brun HeathModesto OrozcoNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Diana Buitrago Mireia Labrador Juan Pablo Arcon Rafael Lema Oscar Flores Anna Esteve-Codina Julie Blanc Nuria Villegas David Bellido Marta Gut Pablo D. Dans Simon C. Heath Ivo G. Gut Isabelle Brun Heath Modesto Orozco Impact of DNA methylation on 3D genome structure
description	Multi-layered epigenetic regulation in higher eukaryotes makes it challenging to disentangle the individual effects of modifications on chromatin structure and function. Here, the authors expressed mammalian DNA methyltransferases in yeast, which have no DNA methylation, to show that methylation has intrinsic effects on chromatin structure.
format	article
author	Diana Buitrago Mireia Labrador Juan Pablo Arcon Rafael Lema Oscar Flores Anna Esteve-Codina Julie Blanc Nuria Villegas David Bellido Marta Gut Pablo D. Dans Simon C. Heath Ivo G. Gut Isabelle Brun Heath Modesto Orozco
author_facet	Diana Buitrago Mireia Labrador Juan Pablo Arcon Rafael Lema Oscar Flores Anna Esteve-Codina Julie Blanc Nuria Villegas David Bellido Marta Gut Pablo D. Dans Simon C. Heath Ivo G. Gut Isabelle Brun Heath Modesto Orozco
author_sort	Diana Buitrago
title	Impact of DNA methylation on 3D genome structure
title_short	Impact of DNA methylation on 3D genome structure
title_full	Impact of DNA methylation on 3D genome structure
title_fullStr	Impact of DNA methylation on 3D genome structure
title_full_unstemmed	Impact of DNA methylation on 3D genome structure
title_sort	impact of dna methylation on 3d genome structure
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/d5ee7c9961b041b8a4708bc652b9e485
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Impact of DNA methylation on 3D genome structure

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