Physical limits to biomechanical sensing in disordered fibre networks

Cells in the connective tissue are surrounded by a heterogeneous network of biopolymers. Here, the authors investigate how such heterogeneity affects cellular mechanosensing by simulating the deformation response of experimental and modelled biopolymer networks to locally applied forces.

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Bibliographic Details
Main Authors: Farzan Beroz, Louise M. Jawerth, Stefan Münster, David A. Weitz, Chase P. Broedersz, Ned S. Wingreen
Format: article
Language:EN
Published: Nature Portfolio 2017
Subjects:
Q
Online Access:https://doaj.org/article/d63624febc554c4b9870ce7fee988307
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