Physical limits to biomechanical sensing in disordered fibre networks

Cells in the connective tissue are surrounded by a heterogeneous network of biopolymers. Here, the authors investigate how such heterogeneity affects cellular mechanosensing by simulating the deformation response of experimental and modelled biopolymer networks to locally applied forces.

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Autores principales: Farzan Beroz, Louise M. Jawerth, Stefan Münster, David A. Weitz, Chase P. Broedersz, Ned S. Wingreen
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/d63624febc554c4b9870ce7fee988307
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spelling oai:doaj.org-article:d63624febc554c4b9870ce7fee9883072021-12-02T17:06:14ZPhysical limits to biomechanical sensing in disordered fibre networks10.1038/ncomms160962041-1723https://doaj.org/article/d63624febc554c4b9870ce7fee9883072017-07-01T00:00:00Zhttps://doi.org/10.1038/ncomms16096https://doaj.org/toc/2041-1723Cells in the connective tissue are surrounded by a heterogeneous network of biopolymers. Here, the authors investigate how such heterogeneity affects cellular mechanosensing by simulating the deformation response of experimental and modelled biopolymer networks to locally applied forces.Farzan BerozLouise M. JawerthStefan MünsterDavid A. WeitzChase P. BroederszNed S. WingreenNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-11 (2017)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Farzan Beroz
Louise M. Jawerth
Stefan Münster
David A. Weitz
Chase P. Broedersz
Ned S. Wingreen
Physical limits to biomechanical sensing in disordered fibre networks
description Cells in the connective tissue are surrounded by a heterogeneous network of biopolymers. Here, the authors investigate how such heterogeneity affects cellular mechanosensing by simulating the deformation response of experimental and modelled biopolymer networks to locally applied forces.
format article
author Farzan Beroz
Louise M. Jawerth
Stefan Münster
David A. Weitz
Chase P. Broedersz
Ned S. Wingreen
author_facet Farzan Beroz
Louise M. Jawerth
Stefan Münster
David A. Weitz
Chase P. Broedersz
Ned S. Wingreen
author_sort Farzan Beroz
title Physical limits to biomechanical sensing in disordered fibre networks
title_short Physical limits to biomechanical sensing in disordered fibre networks
title_full Physical limits to biomechanical sensing in disordered fibre networks
title_fullStr Physical limits to biomechanical sensing in disordered fibre networks
title_full_unstemmed Physical limits to biomechanical sensing in disordered fibre networks
title_sort physical limits to biomechanical sensing in disordered fibre networks
publisher Nature Portfolio
publishDate 2017
url https://doaj.org/article/d63624febc554c4b9870ce7fee988307
work_keys_str_mv AT farzanberoz physicallimitstobiomechanicalsensingindisorderedfibrenetworks
AT louisemjawerth physicallimitstobiomechanicalsensingindisorderedfibrenetworks
AT stefanmunster physicallimitstobiomechanicalsensingindisorderedfibrenetworks
AT davidaweitz physicallimitstobiomechanicalsensingindisorderedfibrenetworks
AT chasepbroedersz physicallimitstobiomechanicalsensingindisorderedfibrenetworks
AT nedswingreen physicallimitstobiomechanicalsensingindisorderedfibrenetworks
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