Physical limits to biomechanical sensing in disordered fibre networks
Cells in the connective tissue are surrounded by a heterogeneous network of biopolymers. Here, the authors investigate how such heterogeneity affects cellular mechanosensing by simulating the deformation response of experimental and modelled biopolymer networks to locally applied forces.
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Nature Portfolio
2017
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oai:doaj.org-article:d63624febc554c4b9870ce7fee9883072021-12-02T17:06:14ZPhysical limits to biomechanical sensing in disordered fibre networks10.1038/ncomms160962041-1723https://doaj.org/article/d63624febc554c4b9870ce7fee9883072017-07-01T00:00:00Zhttps://doi.org/10.1038/ncomms16096https://doaj.org/toc/2041-1723Cells in the connective tissue are surrounded by a heterogeneous network of biopolymers. Here, the authors investigate how such heterogeneity affects cellular mechanosensing by simulating the deformation response of experimental and modelled biopolymer networks to locally applied forces.Farzan BerozLouise M. JawerthStefan MünsterDavid A. WeitzChase P. BroederszNed S. WingreenNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-11 (2017) |
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Science Q |
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Science Q Farzan Beroz Louise M. Jawerth Stefan Münster David A. Weitz Chase P. Broedersz Ned S. Wingreen Physical limits to biomechanical sensing in disordered fibre networks |
description |
Cells in the connective tissue are surrounded by a heterogeneous network of biopolymers. Here, the authors investigate how such heterogeneity affects cellular mechanosensing by simulating the deformation response of experimental and modelled biopolymer networks to locally applied forces. |
format |
article |
author |
Farzan Beroz Louise M. Jawerth Stefan Münster David A. Weitz Chase P. Broedersz Ned S. Wingreen |
author_facet |
Farzan Beroz Louise M. Jawerth Stefan Münster David A. Weitz Chase P. Broedersz Ned S. Wingreen |
author_sort |
Farzan Beroz |
title |
Physical limits to biomechanical sensing in disordered fibre networks |
title_short |
Physical limits to biomechanical sensing in disordered fibre networks |
title_full |
Physical limits to biomechanical sensing in disordered fibre networks |
title_fullStr |
Physical limits to biomechanical sensing in disordered fibre networks |
title_full_unstemmed |
Physical limits to biomechanical sensing in disordered fibre networks |
title_sort |
physical limits to biomechanical sensing in disordered fibre networks |
publisher |
Nature Portfolio |
publishDate |
2017 |
url |
https://doaj.org/article/d63624febc554c4b9870ce7fee988307 |
work_keys_str_mv |
AT farzanberoz physicallimitstobiomechanicalsensingindisorderedfibrenetworks AT louisemjawerth physicallimitstobiomechanicalsensingindisorderedfibrenetworks AT stefanmunster physicallimitstobiomechanicalsensingindisorderedfibrenetworks AT davidaweitz physicallimitstobiomechanicalsensingindisorderedfibrenetworks AT chasepbroedersz physicallimitstobiomechanicalsensingindisorderedfibrenetworks AT nedswingreen physicallimitstobiomechanicalsensingindisorderedfibrenetworks |
_version_ |
1718381702189940736 |