Crystal structure of HIV-1 gp41 including both fusion peptide and membrane proximal external regions.
The HIV-1 envelope glycoprotein (Env) composed of the receptor binding domain gp120 and the fusion protein subunit gp41 catalyzes virus entry and is a major target for therapeutic intervention and for neutralizing antibodies. Env interactions with cellular receptors trigger refolding of gp41, which...
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| Auteurs principaux: | , , , , , |
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| Format: | article |
| Langue: | EN |
| Publié: |
Public Library of Science (PLoS)
2010
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| Accès en ligne: | https://doaj.org/article/d642bbbc55a1477d878fab8a83d1108e |
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