A Novel Mechanism of High-Level, Broad-Spectrum Antibiotic Resistance Caused by a Single Base Pair Change in <named-content content-type="genus-species">Neisseria gonorrhoeae</named-content>

A Novel Mechanism of High-Level, Broad-Spectrum Antibiotic Resistance Caused by a Single Base Pair Change in <named-content content-type="genus-species">Neisseria gonorrhoeae</named-content>

ABSTRACT The MtrC-MtrD-MtrE multidrug efflux pump of Neisseria gonorrhoeae confers resistance to a diverse array of antimicrobial agents by transporting these toxic compounds out of the gonococcus. Frequently in gonococcal strains, the expression of the mtrCDE operon is differentially regulated by b...

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Autores principales: Elizabeth A. Ohneck, Yaramah M. Zalucki, Paul J. T. Johnson, Vijaya Dhulipala, Daniel Golparian, Magnus Unemo, Ann E. Jerse, William M. Shafer
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2011
Materias:
Microbiology
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Acceso en línea:https://doaj.org/article/d64a678538b14a18b274663fa8e4ef37
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