A novel PDX modeling strategy and its application in metabolomics study for malignant pleural mesothelioma

Abstract Background Malignant pleural mesothelioma (MPM) is a rare and aggressive carcinoma located in pleural cavity. Due to lack of effective diagnostic biomarkers and therapeutic targets in MPM, the prognosis is extremely poor. Because of difficulties in sample extraction, and the high rate of mi...

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Auteurs principaux: Zhongjian Chen, Chenxi Yang, Zhenying Guo, Siyu Song, Yun Gao, Ding Wang, Weimin Mao, Junping Liu
Format: article
Langue:EN
Publié: BMC 2021
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Accès en ligne:https://doaj.org/article/d667ec7deb8b4f9ebcd02aef60446ca3
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