Thiamine antagonists trigger p53-dependent apoptosis in differentiated SH-SY5Y cells

Abstract Accumulating evidences suggest that p53 is a key coordinator of cellular events triggered by oxidative stress often associated with the impairment in thiamine metabolism and its functions. However, there are limited data regarding the pursuant feedback between p53 transactivation and thiami...

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Autores principales: Sergiy Chornyy, Yulia Parkhomenko, Nataliya Chorna
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/d66a2e5e989a4fa0a3b84b686578c8b6
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