Hypertension reduces soluble guanylyl cyclase expression in the mouse aorta via the Notch signaling pathway

Abstract Hypertension is a dominating risk factor for cardiovascular disease. To characterize the genomic response to hypertension, we administered vehicle or angiotensin II to mice and performed gene expression analyses. AngII treatment resulted in a robust increase in blood pressure and altered ex...

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Autores principales: Catarina Rippe, Baoyi Zhu, Katarzyna K. Krawczyk, Ed. Van Bavel, Sebastian Albinsson, Jonas Sjölund, Erik N. T. P. Bakker, Karl Swärd
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/d66f40af06af400e8dc806dbae39c231
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