Notoginseng Triterpenes Inhibited Autophagy in Random Flaps via the Beclin-1/VPS34/LC3 Signaling Pathway to Improve Tissue Survival

Notoginseng Triterpenes Inhibited Autophagy in Random Flaps via the Beclin-1/VPS34/LC3 Signaling Pathway to Improve Tissue Survival

Random flaps are widely used in tissue reconstruction, attributed to the lack of vascular axial limitation. Nevertheless, the distal end of the flap is prone to necrosis due to the lack of blood supply. Notoginseng triterpenes (NTs) are the active components extracted from Panax notoginseng, reducin...

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Bibliographic Details
Main Authors: Zhiyang Huang, Xiaobin Luo, Yifan Zhang, Yibo Ying, Xiong Cai, Wenjie Lu, Juan Zhao, Yutian Wang, Wenwei Lin, Yurong Tu, Ziyue Xiang, Qiuji Wu, Shengwu Yang, Sipin Zhu, Xiaoyang Li
Format: article
Language:EN
Published: Frontiers Media S.A. 2021
Subjects:
random flap
notoginseng triterpenes
oxidative stress
autophagy
angiogenesis
Biotechnology
TP248.13-248.65
Online Access:https://doaj.org/article/d68307aa29174d1286f158abce3cc61c
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https://doaj.org/article/d68307aa29174d1286f158abce3cc61c

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