Sialic acid-binding immunoglobulin-like lectin-15 expression on peritumoral macrophages is a favorable prognostic factor for primary central nervous system lymphoma patients

Abstract Sialic acid-binding immunoglobulin-like lectin-15 (Siglec-15) is a new immune checkpoint molecule and its role of primary central nervous system lymphoma (PCNSL) tumor microenvironment has been unclear. We explored the Siglec-15 and programed death-ligand 1 (PD-L1) expression in tumor tissu...

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Autores principales: Hirotaka Fudaba, Yasutomo Momii, Taisei Hirakawa, Kouhei Onishi, Daigo Asou, Wataru Matsushita, Yukari Kawasaki, Kenji Sugita, Minoru Fujiki
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/d68bef7cadce40c1baa011d3079d925c
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