Electro-steric opening of the clc-2 chloride channel gate

Electro-steric opening of the clc-2 chloride channel gate

Abstract The widely expressed two-pore homodimeric inward rectifier CLC-2 chloride channel regulates transepithelial chloride transport, extracellular chloride homeostasis, and neuronal excitability. Each pore is independently gated at hyperpolarized voltages by a conserved pore glutamate. Presumabl...

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Détails bibliographiques
Auteurs principaux: José J. De Jesús-Pérez, G. Arlette Méndez-Maldonado, Ana E. López-Romero, David Esparza-Jasso, Irma L. González-Hernández, Víctor De la Rosa, Roberto Gastélum-Garibaldi, Jorge E. Sánchez-Rodríguez, Jorge Arreola
Format: article
Langue:EN
Publié: Nature Portfolio 2021
Sujets:
Medicine
R
Science
Q
Accès en ligne:https://doaj.org/article/d68ca9a572f94156b3003b15ab5f24b7
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Internet

https://doaj.org/article/d68ca9a572f94156b3003b15ab5f24b7

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