Asymmetric requirement of Dpp/BMP morphogen dispersal in the Drosophila wing disc

Morphogens disperse to pattern tissues and control their growth during development, allowing for the specification of multiple fates across space. Here the authors block dispersal of a morphogen Dpp (BMP2/4) and show that the requirement for Dpp dispersal is much lower than previously thought.

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Autores principales: Shinya Matsuda, Jonas V. Schaefer, Yusuke Mii, Yutaro Hori, Dimitri Bieli, Masanori Taira, Andreas Plückthun, Markus Affolter
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/d69076491bb840b2a2706526450836a4
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spelling oai:doaj.org-article:d69076491bb840b2a2706526450836a42021-11-14T12:36:17ZAsymmetric requirement of Dpp/BMP morphogen dispersal in the Drosophila wing disc10.1038/s41467-021-26726-62041-1723https://doaj.org/article/d69076491bb840b2a2706526450836a42021-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-26726-6https://doaj.org/toc/2041-1723Morphogens disperse to pattern tissues and control their growth during development, allowing for the specification of multiple fates across space. Here the authors block dispersal of a morphogen Dpp (BMP2/4) and show that the requirement for Dpp dispersal is much lower than previously thought.Shinya MatsudaJonas V. SchaeferYusuke MiiYutaro HoriDimitri BieliMasanori TairaAndreas PlückthunMarkus AffolterNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Shinya Matsuda
Jonas V. Schaefer
Yusuke Mii
Yutaro Hori
Dimitri Bieli
Masanori Taira
Andreas Plückthun
Markus Affolter
Asymmetric requirement of Dpp/BMP morphogen dispersal in the Drosophila wing disc
description Morphogens disperse to pattern tissues and control their growth during development, allowing for the specification of multiple fates across space. Here the authors block dispersal of a morphogen Dpp (BMP2/4) and show that the requirement for Dpp dispersal is much lower than previously thought.
format article
author Shinya Matsuda
Jonas V. Schaefer
Yusuke Mii
Yutaro Hori
Dimitri Bieli
Masanori Taira
Andreas Plückthun
Markus Affolter
author_facet Shinya Matsuda
Jonas V. Schaefer
Yusuke Mii
Yutaro Hori
Dimitri Bieli
Masanori Taira
Andreas Plückthun
Markus Affolter
author_sort Shinya Matsuda
title Asymmetric requirement of Dpp/BMP morphogen dispersal in the Drosophila wing disc
title_short Asymmetric requirement of Dpp/BMP morphogen dispersal in the Drosophila wing disc
title_full Asymmetric requirement of Dpp/BMP morphogen dispersal in the Drosophila wing disc
title_fullStr Asymmetric requirement of Dpp/BMP morphogen dispersal in the Drosophila wing disc
title_full_unstemmed Asymmetric requirement of Dpp/BMP morphogen dispersal in the Drosophila wing disc
title_sort asymmetric requirement of dpp/bmp morphogen dispersal in the drosophila wing disc
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/d69076491bb840b2a2706526450836a4
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